Atypical teratoid/rhabdoid tumors in adult patients: CT and MR imaging features.

نویسندگان

  • L Han
  • Y Qiu
  • C Xie
  • J Zhang
  • X Lv
  • W Xiong
  • W Wang
  • X Zhang
  • P Wu
چکیده

Primary AT/RT is a rare highly malignant tumor of the CNS, usually occurring in children younger than 5 years of age. The objective of this study was to characterize the CT and MR imaging findings in a series of 5 adult patients with pathologically proved AT/RT. All 5 AT/RTs were supratentorial. In 2 patients who underwent nonenhanced CT, the tumors appeared isoattenuated, and 1 of the 2 tumors contained calcifications. Solid portions of the tumors on MR imaging were isointense on T1-weighted, T2-weighted, and FLAIR images, and 1 case showed restricted diffusion on DWI. The tumors also demonstrated a bandlike rim of strong enhancement surrounding a central cystic area on contrast-enhanced T1-weighted imaging. One tumor was associated with destruction of the calvaria. Although AT/RTs can have nonspecific findings, the tumors in our series were large and isointense on T1-weighted, T2-weighted, and FLAIR images with central necrosis and prominent rim enhancement.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Imaging findings of CNS atypical teratoid/rhabdoid tumors.

Four patients with brain tumors were diagnosed with atypical teratoid/rhabdoid tumors and underwent CT and MR imaging. For all tumors, aggressive features were shown by imaging studies and included hydrocephalus, apparent invasion of the adjacent brain and dura, and marked mass effect. The striking heterogeneity of the atypical teratoid/rhabdoid tumor shown by imaging studies reflects the histo...

متن کامل

Bone involvement in atypical teratoid/rhabdoid tumors of the CNS.

SUMMARY Destruction of the bony structures of the skull is rare in primary tumors of the CNS. In low-grade gliomas, modeling of the skull is caused by slow growth and chronic pressure. Bony destruction is exceptional even in highly malignant gliomas. Atypical teratoid/rhabdoid tumors of the CNS are highly malignant neoplasms diagnosed with an increasing frequency, mainly in young children. On i...

متن کامل

Atypical teratoid/rhabdoid tumor of the cerebellum: report of two infantile cases.

Atypical teratoid/rhabdoid tumor of the CNS is an aggressive infantile neoplasm of uncertain origin. In our two infantile cases, this tumor presented as a bulky cerebellar hemispheric mass with significant mass effect to the fourth ventricle and brain stem. Although the attenuation on CT and signal intensity characteristics at MR imaging of this tumor were similar to those of vermian medullobla...

متن کامل

Atypical Teratoid/Rhabdoid Tumors in Adults: A Case Report and Treatment-Focused Review

UNLABELLED Atypical teratoid/rhabdoid tumor is predominantly a childhood tumor and has only been rarely reported in adults; therefore, treatment regimens are often extrapolated from the pediatric experience. Typically, children are treated with craniospinal radiation therapy which is often followed by systemic chemotherapy. Employing pediatric regimens to treat this tumor in adult patients pose...

متن کامل

Oncolytic Herpes Virus rRp450 Shows Efficacy in Orthotopic Xenograft Group 3/4 Medulloblastomas and Atypical Teratoid/Rhabdoid Tumors

Pediatric brain tumors including medulloblastoma and atypical teratoid/rhabdoid tumor are associated with significant mortality and treatment-associated morbidity. While medulloblastoma tumors within molecular subgroups 3 and 4 have a propensity to metastasize, atypical teratoid/rhabdoid tumors frequently afflict a very young patient population. Adjuvant treatment options for children suffering...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • AJNR. American journal of neuroradiology

دوره 32 1  شماره 

صفحات  -

تاریخ انتشار 2011